Thursday, May 10, 2012

Obama: I support same-sex marriage (CNN)

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Renew Your Home by Remodeling and Home Improvement

A home is analogous to heaven and is the most loved asset of many. Riverside contractors help the homeowners in finding home repair and improvement professionals. These professionals trip customer?s residence and have a look at the smash up that has to be repaired or the room that has to be remodeled. For an individual looking for repairing his home there can be no good option than this as he/she will be provided with complete guidance and assistance in finding the services that accomplishes their needs and satisfy their criteria of requirements at a very cheap and affordable price. Numerous categories of contractors are available here that include cabinets, chimney and fireplace, concrete, drywall, fencing, flooring, general contractors, kitchen remodelers, electrical, Roofing contractors etc. After selecting the category of contractor, a list appears with the names of all the contractors providing the selected category services in the area.

The customer can now opt for the contractor he/she wishes to by reading his profile and can contact him/her through the contact details mentioned. There is a facility of comparison available and in case the customer has problem in making decision for the contractor he can make multiple choices and compare between them. There repair assistants and remodelers schedule meetings with the customers and visit their homes on a decided date. They check for damage and have a look at the sort of repair required not just this but they also ask the homeowners regarding what kind of changes they are seeking, their advice on remodeling etc. Based on the details mentioned by the customer they prepare a map of the room and once the homeowner is satisfied by the design the phase for remodeling starts. Riverside contractors enjoy good reputation among people for setting up the best repairs and remodeling in CA at the least possible prices in the market.

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Live at 'DWTS': What you didn't see on TV

Adam Taylor / ABC

Val Chmerkovskiy took off his vest after his samba with big bro Maks and actress Melissa Gilbert. And it seems a lucky audience member went home with the garment.

By Anna Chan

The glitz! The glam! "Dancing With the Stars" looks pretty amazing when it airs live on TV, but the audience at home misses out on some of the fun tidbits that can be seen only at the live tapings. Here are a few of the things I saw when I attended my first live "DWTS" shows on May 7 and 8:

1. First of all, don't even try to sneak your cell phone in. By the time the audience was lined up and ready to enter the ballroom, there were two crates filled with confiscated phones. (The gadgets were tagged and owners given tickets to retrieve them later.) Also, get rid of that gum. Otherwise, the ushers will make you spit it into a little paper cup later.

2. The ballroom looks gigantic on television, but it's not as huge in person. (Still quite impressive, though!) On the other hand, the ginormous mirror ball that hangs above the dance floor? That thing is even more massive than it looks on TV.

3. Prior to the show's start on Monday, Carrie Underwood pretaped a performance in the ballroom. (Air date unknown.) The audience was instructed on when to start cheering -- when she starts singing, and when the troupe dancers hit the floor. And before the live show kicked off on Tuesday, R&B star Chris Brown was on hand to pretape his performance, which aired during the elimination show. The singer did his set two and?a quarter times. That quarter was thanks to the audio cutting out early in the second take. See why these performances aren't live?

4. It's not only the pro hoofers and stars who have slick dance-floor moves. As each judge was announced to the ballroom crowd minutes before the live show Monday, Carrie Ann Inaba, Len Goodman and Bruno Tonioli each showed off a few steps before taking their seats on the panel. Carrie Ann shimmied, Len proved he's still got the moves and Bruno showed off some ... umm ... manly hip action!

5. During the commercial breaks, the pros and their partners took advantage of the off-camera time and could be seen practicing their moves in the CelebAquarium. Stars Roshon Fegan and William Levy seemed to make the most of the time on performance night, and it paid off. The two men ended up with the highest scores for their first dances. (Unfortunately for Roshon, it didn't do him much good in the end.)

6. Also during the commercial breaks? The stars and pros who had just performed and were waiting in the CelebAquarium with co-host Brooke Burke-Charvet for the scores would have their brows wiped down by the crew and makeup reapplied. Don't want to be dripping too much when the cameras zoom in for a reaction to the scores!

7. As you may have seen, after Melissa Gilbert and the Chmerkovskiy brothers performed the samba for their trio dance, Val took off his vest and flung it off to the side of the dance floor during the judges' critiques. Seems some lucky audience member may have picked it up and kept it for themselves! During the commercial breaks, it was announced several times that the show's costume department would need the item back, but the Chmerkovskiy-blessed garment didn't seem to make a reappearance.

8. Oh that Tom Bergeron! The host showed off his sense of humor on Tuesday prior to the live show. Moments before the show started, he stared into the cameras with a deer-in-the-headlights look on his face and mouthed, "I'm so nervous!" Later, while pretaping some audio for a future broadcast, Tom teased, "And the winner of season 14 is ... your mama!"

9. There is one big bonus to watching at home instead of in the ballroom: You can actually hear everything that's said. All those witty quips Tom makes? The audience doesn't hear any of it unless he's standing right next to them. The judges' comments? You can hear those very, very faintly depending on where your seat is (and if you have amazing hearing), but once the crowd starts cheering or booing, forget it. Hope you set that DVR to record.

If you were to attend a taping, what would you like to see? Share your thoughts on our Facebook page!

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Flavonoid compound found in foods and supplements may prevent the formation of blood clots, study suggests

ScienceDaily (May 8, 2012) ? A compound called rutin, commonly found in fruits and vegetables and sold over the counter as a dietary supplement, has been shown to inhibit the formation of blood clots in an animal model of thrombosis.

These new findings, led by investigators at Beth Israel Deaconess Medical Center (BIDMC) and published in online in The Journal of Clinical Investigation (JCI), identify a novel strategy for preventing thrombosis, and help pave the way for clinical testing of this popular flavonoid as a therapy for the prevention and treatment of stroke and heart attack, as well as deep venous thrombosis (DVT) and pulmonary embolism.

"It's not always fully appreciated that the majority of Americans will die as the result of a blood clot in either their heart or their brain," says senior author Robert Flaumenhaft, MD, PhD, an investigator in the Division of Hemostasis andThrombosis at BIDMC and Associate Professor of Medicine at Harvard Medical School. "Approximately half of all morbidity and mortality in the United States can be attributed to heart attack or stroke."

The study focused on protein disulfide isomerase (PDI) which is found in all cells. Investigators in BIDMC's Division of Hemostasis and Thrombosis had previously shown that PDI is rapidly secreted from both platelets and endothelial cells during thrombosis, when a clot forms in a blood vessel, and that inhibition of PDI could block thrombosis in a mouse model.

"This was a transformative and unanticipated finding because it identified, for the first time, that PDI is secreted from cells in a live animal and is a potential target for preventing thrombosis," says Flaumenhaft. However, because intracellular PDI is necessary for the proper synthesis of proteins, the scientists had to identify a specific compound that could block the thrombosis-causing extracellular PDI -- without inhibiting the intracellular PDI.

They began by conducting a high-throughput screen of a wide array of compounds to identify PDI inhibitors. Among the more than 5,000 compounds that were screened, quercetin-3-rutinoside (rutin) emerged as the most potent agent. "Rutin was essentially the champion compound," says Flaumenhaft.

A bioflavonoid that is naturally found in many fruits, vegetables and teas including onions, apples and citrus fruits, rutin is also sold as an herbal supplement, having received a special designation for safety from the U.S. Food and Drug Administration (FDA). Surprisingly, studies of the rutin molecule demonstrated that the same part of the molecule that provides rutin with its ability to inhibit PDI also prevents the compound from entering cells."That finding explained how this compound can be both a potent inhibitor of PDI and a safe food supplement," says Flaumenhaft. "Our next questions were, 'Is this compound anti-thrombotic? Can it prevent blood clots?'"

The team went on to test rutin in a mouse model of thrombosis. Because they knew that humans would be taking rutin in pill form, they included studies in which the compound was administered orally and determined that it successfully retained its anti-thrombotic properties when it was metabolized following oral ingestion.

"Rutin proved to be the most potently anti-thrombotic compound that we ever tested in this model," says Flaumenhaft. Of particular note, rutin was shown to inhibit both platelet accumulation and fibrin generation during thrombus formation. "Clots occur in both arteries and in veins," explains Flaumenhaft. "Clots in arteries are platelet-rich, while those in veins are fibrin-rich. This discovery suggests that a single agent can treat and prevent both types of clots."

Even with the use of existing anti-clotting therapies, such as aspirin, clopidogrel (Plavix) and warfarin (Coumadin), each year there are approximately 400,000 recurrent episodes among patients who previously experienced a stroke or heart attack, says Flaumenhaft.

"A safe and inexpensive drug that could reduce recurrent clots could help save thousands of lives," he adds. "These pre-clinical trials provide proof-of-principle that PDI is an important therapeutic target for anti-thrombotic therapy, and because the FDA has already established that rutin is safe, we are poised to expeditiously test this idea in a clinical trial, without the time and expense required to establish the safety of a new drug."

The original research that identified this mechanism as well as the identification of PDI as a drug target of rutin was supported primarily by grants from the National Heart, Lung and Blood Institute of the National Institutes of Health (NIH) and also from the American Heart Association. Additional support came from the European Hematology Association-American Society of Hematology and the Foundation for Women's Wellness.

Study coauthors include BIDMC investigators Reema Jasuja (first author), Freda H. Passam, Daniel R. Kennedy, Sarah H. Kim, Lotte van Hessem, Lin Lin, Sheryl R. Bowley, Sucharit S. Joshi, James R. Dilks, Bruce Furie and Barbara C. Furie, all of the Division of Hemostasis and Thrombosis.

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The above story is reprinted from materials provided by Beth Israel Deaconess Medical Center.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Reema Jasuja, Freda H. Passam, Daniel R. Kennedy, Sarah H. Kim, Lotte van Hessem, Lin Lin, Sheryl R. Bowley, Sucharit S. Joshi, James R. Dilks, Bruce Furie, Barbara C. Furie, Robert Flaumenhaft. Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. Journal of Clinical Investigation, 2012; DOI: 10.1172/JCI61228

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Wednesday, May 9, 2012

Atlantic invests in the future of agriculture : Atlantic

Posted by admin on May 8, 2012 ? ?

In photo are the 26 farmers who graduated from the 2nd annual Farmer Enterprise Training Programme run by the University of Trinidad and Tobago, facilitated by the Ministry of Food Production and Land and Marine Affairs, and sponsored by LNG production company Atlantic. Front row seated includes (left to right): Ms. Leela Watti Rastogi, the Ministry's Director, Regional Administration South; Ms. Toni Sirju-Ramnarine, Head, Sustainability and Corporate Communications, Atlantic; Ms. Stephanie Elder Alexander, the Ministry's Deputy Permanent Secretary; and Ms. Jillian Singh, Product Assistant, University of Trinidad and Tobago.

LNG production company Atlantic will continue to invest in the training of farmers and agricultural entrepreneurs as an initiative to help reduce Trinidad and Tobago?s reliance on food imports.

This was announced by Toni Sirju-Ramnarine, Atlantic?s Head of Sustainability and Corporate Communications, who was speaking at the recently held Graduation Ceremony for the 2nd annual Atlantic Farmer Enterprise Training Programme.

Addressing the Programme?s twenty-six (26) graduates, Ms. Sirju-Ramnarine explained that while it may seem strange for a company that processes natural gas to be interested in farming and food production, Atlantic saw it as an opportunity to help strengthen local capacity and re-energise agricultural enterprise at the community level.

?Food is not a luxury, but a necessity,? Ms. Sirju-Ramnarine said. ??It is our expectation that your commercial farming enterprises will decrease Trinidad and Tobago?s vulnerability to global market forces and reliance on food imports.?

Ms. Sirju-Ramnarine described the Farmer Enterprise Training Programme as straddling the line between traditional agricultural techniques and modern approaches to viable commercial agricultural business.

?Today?s farming communities must be willing to adopt new approaches and explore new opportunities to take your product from field to market, if they are to be sustainable,? Ms. Sirju-Ramnarine said. ??In your grandparents? time, understanding marketing, sponsorships and e-business were not required for agricultural enterprise. ?However to be competitive in today?s market, one has to be one step ahead.?

The Atlantic Farmer Enterprise Training Programme was established in 2010 by Atlantic in partnership with the University of Trinidad and Tobago and the Ministry of Food Production and Land and Marine Affairs. ?The programme focuses on the development of ?agri-entrepreneurs? in the Southwest Peninsula and wider Trinidad and Tobago. ?The three-month course exposes young farmers to the latest techniques in their areas of agriculture specializations, as well as skills in business development and the use of computer applications in modern agri-business.

For the 2012 programme, twenty-six (26) farmers and entrepreneurs participated, with specializations in food crops, tree crops, agri-processing, vegetables, apiculture and poultry.

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Afghan photographers eschew electronics for wooden camera portraits (video)

If retro-style snaps are worth a billion dollars à la Instagram, what does that say about the value of real prints taken with pre-WWII gear? Reminding us that early cameras were photochemical and shutterless, Kabul is home to two lone holdouts who still practice the 75-year-old art of wooden camera photography. Due to a ban on picture-taking by the Taliban, and then an influx of cheap digital cameras, the number of practitioners of kamra-e-faoree has steadily dwindled. But thanks to the Afghan Box Camera Project, the legacy left by these artisans is being preserved -- not least in the video above. Discover how it all works and then leave the faux-vintage to the hipsters.

Afghan photographers eschew electronics for wooden camera portraits (video) originally appeared on Engadget on Wed, 09 May 2012 14:16:00 EDT. Please see our terms for use of feeds.

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From "Merkozy" to "Merde"? (Americablog)

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