Source: http://www.thehollywoodgossip.com/2012/12/katherine-webb-dating-aj-mccarron/
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Saturday, December 29, 2012
CCOTY 1968 Nomination: NSU Ro80?The Tragic Automotive ...
In the Pantheon of automotive gods and godesses, the Ro80 occupies a long-guaranteed spot. Simply put, it is one of the boldest, most influential and revolutionary cars ever?despite being a dismal failure. Its tragic story comes straight from the Greek legends; perhaps it should have been called the Ikarus.
NSU was a small maker of little cars and motorcycles. Both their 600cc Prinz and slightly larger 1000/1200 were notable for their Corvair-like looks, as well as for the air-cooled rear engine that was tucked in close to the rear wheels. But as incomes grew throughout the ?60s, the German (and European) market was quickly expanding into larger classes, and NSU made a bold double bet.
Their decision to expand up-market with a new four-door sedan was certainly ambitious. And got even more so: What was initially intended as a Ford Taunus competitor was later scaled up to directly compete against the smaller Mercedes models and BMW?s Neue Klasse. Ambitious indeed?but that was the relatively easy part.
Having signed a development contract with Felix Wankel, NSU co-developed what became the modern rotary engine (Wankel?s original design, which included a rotating engine case, was scrapped). Their new engine debuted in the limited-production NSU Spider (seen above in an interesting contemporary street shot).
Only 2,375 of the single-rotor, 50 hp cars were built, more or less as rolling test labs. It wasn?t long before the engine exhibited problems, mostly with the tricky apex seals?something that should have given NSU pause about powering the Ro80 with a larger, two-rotor version placed ahead of the front (driving) wheels.
The Ro80?s 995cc, twin-rotor engine was rated at 113 hp (115 PS). Because of the rotary?s tendency to run rough on overrun with a manual transmission, NSU turned to a Saxomat semi-automatic transmission, built by Fichtel and Sachs (and also offered by Porsche as the Sportomatic). It combined an shift-lever actuated automatic clutch with a torque convertor. Although there was no clutch pedal, one shifted through the three gears manually, much like the automatic stick shift found in some contemporary VW Beetles.
Inboard front disc brakes rounded out the very ambitious drive train, which was designed to shine on the German autobahns that were mostly uncrowded in the early- and mid-sixties. Unfortunately, the drive train was less ideally suited to dense traffic and city driving.
You already know where this is going: The Ro80?s engine was woefully underdeveloped in terms of durability. It became a nightmare of warranty costs and earned such a bad reputation that NSU was eventually forced to accept a takeover by Audi. That said, let?s focus instead on one of its indisputably superb qualities: The very enduring influence of its superb body design.
The Ro80 body design was an in-house job executed by Claus Luthe. It is utterly brilliant, even if some of its proportions seem a wee bit eccentric from certain angles. But that just adds to its allure, at least in the eyes of its admirers.
Needless to say, you?re looking at the mother of all Audis here?and the Taurus and, to some extent, just about every modern sedan. The drooping front nose, the overall wedge shape ending in a tall tail, the gracefully arching roof. The R080?s vast and enduring influence is unmistakable. And its aerodynamic Cd of 0.355 was excellent for the times.
The Ro80 was the significant link between that other goddess, the 1955 Citroen DS, and just about everything that followed. The ?utterly uncompromising shape of the DS was hardly conducive to cribbing; it was certainly revered, but mostly at a distance. In contrast, the R080?s design was seen as a more pragmatic way forward, as it incorporated the key advantages of the Citroen?s long-wheelbase and aerodynamic design in a more palatable and practical solution.
Only 37,398 Ro80s were built over its decade-long lifespan. NSU tried valiantly to address the severe issues involving engine life (some engines showed apex-seal wear after as little as 15,000 miles and were worn out by 30,000).?Still, it was a losing battle. Although it would later be fought with relatively greater success by Mazda, similar issues plagued their rotaries as well.
Many frustrated?owners refitted their Ro80s with the little Ford V4,?which was the only engine that fit. It was an ironic choice: The rotary?s biggest asset was turbine-smooth running, and the Ford V4 was one of the roughest engines ever built. Of course, Saab took the same road with their two-stroke 96, but did so officially.
A modest number of Ro80s were sold in the U.S. I?ve never seen one, nor do I expect to, so the prospect of an in-depth?write up?here is not terribly likely. But ateupwithmotor just recently published his article on the Ro80, and it is (as always) very comprehensive?and it?s right on time for the Ro80?s CCOTY nomination, as its historical value is more appreciated than ever (during the late seventies, one could hardly give an Ro80 away). The Ro80 was COTY in Europe in 1968, beating out the Fiat 125 (second) and Jensen FF (AWD).
Source: http://www.curbsideclassic.com/blog/ccoty-1968-nomination-nsu-ro80-the-tragic-automotive-goddess/
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Friday, December 28, 2012
7 ways to be indispensable at work in 2013
51 min.
The New Year is, for many, a time of change and resolutions. Be thinner! Be richer! Meet the love of your life!
For others, our hopes and dreams are more measurable. Whether it?s a 10 percent pay raise you?re after or moving one step closer to the corner office, forget job-hopping.?In 2013, staying put and amping up your performance at work is the way to make it happen.
?The prevailing wisdom has been that to get ahead, you should learn something from one company and move on?and up?at the next,? says Brian Kropp, a managing director at?CEB, an executive advisory firm?which offers data analysis of more than 50,000 employee surveys from 10,000 organizations. ?But that only produces short-term effects. In the new workplace we?re seeing greater emphasis on relationships,? he says, which means veteran employees are at a far greater advantage. According to CEB research,?longer-tenured workers are beginning to rise to positions of success more quickly than those who move every few years.
So what does this mean for 2013 career resolutions? Ditch the job boards and set to work making yourself an indispensable employee.
?Being indispensable is about being the best,? says Lucy Leske, vice president and co-director,?education?practice at the?executive search firm, Witt/Kieffer. ?If you?re always striving to be a better, more valuable contributor, people will inevitably take note and you?will?get ahead.?
Without further pontification, seven simple strategies to becoming indispensable in 2013.
Be flexible
?The odds are that the way you?ll do work on January 1st?won?t be the way you?ll be doing work on December 31st,? says Kropp. According to?CEB?research, more than 50 percent?of employees say they have experienced ?significant change? at work in the past 12 months, from reorganizations to new workflows to massive layoffs. ?Make sure that your boss sees you are someone who can get the job done no matter what?s happening around you.?
Stay current
?If you?re not regularly reading about industry trends in trade, business and general publications, checking out online sources and staying current on trends in your industry, you?re compromising your career growth,? says Leske. ?Keeping up on trends, but more importantly, being able to apply those trends to your organization, demonstrates your understanding if its place within the industry.?
Don?t be a loner
In the new workplace, 40 percent of employees work with more than 20 people on a given day, and more than 80 percent work with 10 according to?CEB?research. ?The idea that you can be an individual contributor and be successful is an idea of the past,? says Kropp. ?Fitting within the network of the workplace is a part of the new definition of a great employee.?
Be a thought leader
All of that knowledge you?ve gained by reading up on the industry? Leske says to make a habit of sharing it. ?Write articles, make presentations, serve on panels or blog,? she says. ?People need to have confidence in you that you know what you?re doing and that you?re willing to use it to help other peoples? problems.?
Prioritize
?It?s really easy to add more things to your to-do list but just as critical?if not more so?to know what to take off,? says Kropp. It?s no secret that work can be an overwhelming place, particularly in a post-recession environment where Kropp says the number of direct reports answering to any given manager has increased by an average of 50 percent in the past five years. Good decision making, delegating and prioritization are the signs of an effective leader, no matter your position within the organizational matrix.
Slideshow: How To Be Better At Your Job In 2013
Seek opportunities for management experience
Speaking of managers, Leske advises that you actively pursue any opportunity for managing employees, no matter how small and trivial (or large and daunting) the task may seem. ?There?s a difference between begging for these opportunities and raising your hand,? she warns, ?but if someone says there?s a job to be done, raise your hand first and ask for help later. The biggest mistake is passing up the opportunity.?
Make friends with the IT guy
The average number of work-related emails we receive each day has increased fourfold since 2005, underscoring the explosive importance of technology in the office. This makes the IT department not just a vital team in the workforce, but an essential ally to any employee reaching for success as with their help you can avoid unnecessary downtime due to tech failures.
But Kropp adds that it isn?t just the IT team who have become increasingly important within the workplace. ?Making friends with admins is an important move as well,? he says. As workflows have changed in the workplace of 2013 CEB reports that power, authority and decision making is cropping up in some unexpected places. ?The administrative assistant of the CEO decides what?s on his or her schedule,? he points out. Underestimating their authority?or missing the opportunity to develop a strong relationship with that person is a judgment lapse no indispensable employee would miss.
More from Forbes
Source: http://www.nbcnews.com/business/7-ways-be-indispensable-work-2013-1C7660249
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Speedy boson machine could bridge classic and quantum computing
2 hrs.
A new type of machine could rival quantum computers in exceeding the power of classical computers, researchers say.
Quantum computers?rely on the bizarre properties of atoms and the other construction blocks of the universe. The world is a fuzzy place at its very smallest levels ? in this realm where?quantum physics?dominates, things can seemingly exist in two places at once or spin in opposite directions at the same time.
The new computers rely on "boson" particles, and resemble quantum computers, which differ from traditional computers in important ways. Normal computers represent data as ones and zeroes, binary digits known as bits that are expressed by flicking switch-like transistors on or off. Quantum computers, however, use quantum bits, or qubits (pronouced "cue-bits"), that can be on and off at the same time, a state known as "superposition."
This allows the machines to carry out two calculations simultaneously. Quantum physics permits such behavior because it allows for particles that can exist in two places at once or spin in opposite directions at the same time.?[Experiment Demonstrates Possibility of Quantum Internet]
Flash interactive: How quantum computers work
In principle, quantum computers could solve certain problems much faster than can?classical computers, because the quantum machines could run through every possible combination at once. A quantum computer with 300 qubits could run more calculations in an instant than there are atoms in the universe.
However, keeping qubits in superposition is challenging, and the problem grows more difficult as more qubits are involved. As such, building quantum computers that are more powerful than classical computers has proven very difficult.
Now, though, two independent teams of scientists have built a novel kind of device known as a boson-sampling computer. Described as a bridge between classical and quantum computers, these machines also make use of the bizarre nature of quantum physics. Although boson-sampling computers theoretically offer less power than quantum computers are capable of producing, the machines should still, in principle, out-perform classical computers in certain problems.
In addition, a boson-sampling computer does not require qubits. As such, "it's technologically far simpler to create than building a full-scale quantum computer," said researcher Matthew Broome, a quantum physicist at the University of Queensland in Australia.
Boson-sampling computers are actually a specialized kind of quantum computer (which is known more formally as a universal quantum computer).
"The main difference between boson-sampling computers and universal quantum computers is that boson-sampling quantum computers can't solve a universal set of problems like universal quantum computers can," Broome said. "But they are still conjectured to be able to solve problems that would be massively intractable for classical computers. Boson sampling computers are an intermediate model of a quantum computer."
Boson-sampling computers are not based on qubits, but on particles called?bosons. "In our case, we use photons," said researcher Ian Walmsley, a quantum physicist at the University of Oxford in England. Photons are the packets of energy that make up light, and are one type of boson.
Gallery: What the heck is a boson?
Broome and Walmsley were in separate groups that each devised a boson-sampling computer, based off concepts first described by theoretical computer scientist Scott Aaronson at MIT. The computers involve multiple devices that can each generate single photons. The photons are inserted into a network where they can interact with one another. They emerge from outputs equipped with sensors to analyze the particles.
The task of calculating which outputs these photons will emerge from, an operation known as boson sampling, grows well beyond the capabilities of classical computers the more photons are involved. The new computers accurately resolved what paths the photons would take ? three photons with Broome and his colleagues' machine and four in Walmsley and his collaborators' device.
Since boson-sampling computing is in its infancy, it remains uncertain whether these computers can solve problems beyond boson sampling. Still, this research suggests that computers based on quantum physics could indeed tackle problems beyond the reach of classical computers.
Year in Science: Higgs boson takes the prize
Previously, there was nothing to say "that anything you can do on a quantum computer you can't do on a normal computer, which leaves in question the necessity for quantum computers," Broome said. "Now, with boson sampling, we're coming up with machines based on quantum physics that can attack problems strongly believed to be intractable for classical computers."
In the future, "it would be great to push these computers toward more photons to tackle problems that would be challenging to simulate on normal computers," study coauthor Walmsley added. Using about 20 to 30 photons would?be a problem?beyond the capabilities of classical computers.
Both research teams detailed their findings online Dec. 20 in the journal Science.
Copyright 2012?InnovationNewsDaily, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Thursday, December 27, 2012
Cellular fuel gauge may hold the key to restricting cancer growth
Dec. 27, 2012 ? Researchers at McGill University have discovered that a key regulator of energy metabolism in cancer cells known as the AMP-activated protein kinase (AMPK) may play a crucial role in restricting cancer cell growth. AMPK acts as a "fuel gauge" in cells; AMPK is turned on when it senses changes in energy levels, and helps to change metabolism when energy levels are low, such as during exercise or when fasting. The researchers found that AMPK also regulates cancer cell metabolism and can restrict cancer cell growth.
The discovery was made by Russell (Rusty) Jones, an assistant professor at McGill's Goodman Cancer Research Centre and the Department of Physiology, Faculty of Medicine. Jones along with his team is the first to show that AMPK can act as a tumour suppressor in animals. The research will be published December 27 in the journal Cell Metabolism.
"Cancer is a disease in which cells lose their normal restraints on growth and start to divide uncontrollably. But, in order for cells to grow quickly they need enough energy to complete the task," Jones explained. "AMPK acts like the fuel gauge in your car -- it lets the body know when energy levels are low, and stops cell growth until there is enough gas in the tank. We wanted to see if this fuel gauge could affect the development and progression of cancer. We found that mice lacking AMPK developed tumours faster, suggesting that AMPK is important for keeping tumour development in check, at least for some types of cancer." For this study, Jones' team focused specifically on a type of blood cancer known as lymphoma. They discovered that the protein Myc, which is activated in more than half of all cancers, could promote lymphoma more rapidly when mice were deficient for AMPK.
One of the ways cancer cells support their enhanced rate of growth is by changing their metabolism, or how they generate energy. Cancer cells are different from normal cells in our body because they preferentially use sugar to fuel their growth. Jones discovered that AMPK plays a specific role in restricting cancer cells' ability to use sugar to fuel their growth. "For cancer cells with low AMPK levels, their metabolism goes into overdrive," explained Prof. Jones. "They use sugar more efficiently, allowing them to grow faster. These results suggest that turning on AMPK in cancer cells may be one way that we can restrict cancer growth."
Jones' breakthrough builds on his previous discovery that the widely prescribed medication metformin, a common diabetes drug, can restrict tumour cell growth. The results bring promise that common therapeutics that turn on AMPK and alter cellular metabolism, such as metformin, may become novel tools for cancer therapy. Jones and his colleagues at McGill are currently exploring clinical applications based on this research.
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The above story is reprinted from materials provided by McGill University, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Brandon Faubert, Gino Boily, Said Izreig, Takla Griss, Bozena Samborska, Zhifeng Dong, Fanny Dupuy, Christopher Chambers, Benjamin?J. Fuerth, Benoit Viollet, Orval?A. Mamer, Daina Avizonis, Ralph?J. DeBerardinis, Peter?M. Siegel, Russell?G. Jones. AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In?Vivo. Cell Metabolism, 2012; DOI: 10.1016/j.cmet.2012.12.001
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/S3OtxBo-Q-Q/121227130327.htm
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